Admission hyperglycemia is associated with poor prognosis in patients with acute myocardial infarction (AMI), but the effects of baseline diabetes status on this association still remain fully unexplained. Recent research published in ‘Cardiovascular Diabetology’ investigated the impact of admission hyperglycemia on short and long-term outcomes in AMI patients with and without diabetes.

This retrospective cohort study was conducted in 3330 patients with regard to first-time AMI.They were divided into four groups according to diabetes status-specific cutoff values of fasting blood glucose (FBG) identified by restricted cubic spline. Short-term outcomes included in-hospital death and cardiac complications. Long-term outcomes were all-cause mortality and major adverse cardiovascular events (MACE).

According to the researchers, the inflection points of fasting Blood Glucose (FBG) level for poor prognosis were 5.60 mmol/L for patients without diabetes and 10.60 mmol/L for patients with diabetes. Admission hyperglycemia was identified as an independent predictor of worse short and long-term outcomes in AMI patients, with or without diabetes.