It is known from previous studies that breakfast helps to reduce hyperglycemia after the second meal of the day. This study published in American Diabetes Association official journal 'Diabetes Care' gives evidence that a high protein- low carb pre breakfast snack can go a long way in controlling breakfast hyperglycemia in subjects with Type 2 diabetes. This study assumes special significance since postprandial hyperglycemia is a major cause of death in subjects with Type 2 diabetes.
Researchers studied 10 men and women with diet- and/or metformin-controlled Type 2 diabetes. Metabolic changes after breakfast were analysed between 2 days: breakfast taken only and soya-yogurt snack taken prior to breakfast.
The results showed that there was a significant lower rise in plasma glucose on the snack day. This study demonstrated for the first time that the provision of a practical, high-protein, low-carbohydrate snack prior to breakfast reduced by 40%, the postprandial plasma glucose increment in people with Type 2 diabetes. The significance of this observation is that a more practical means of improving glucose tolerance could potentially be of therapeutic benefit in people with Type 2 diabetes.
Researchers observed no effect of the prior snack on insulin secretion after breakfast. The mechanism underlying the second-meal effect is due to suppression of plasma Free Fatty Acids (FFA), allowing greater storage of glucose as muscle glycogen. They had previously demonstrated a strong negative correlation between the decrease of pre-prandial plasma FFA levels and the post-meal glucose increment. In the present study, a significant positive correlation was found between pre-breakfast plasma FFA and the rise in postprandial plasma glucose concentration.
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