Issue 28, February 2011
5. Safflower oil improves glycemic control and lipids in Type 2 diabetic women

    Researchers from the The Ohio State University, Columbus, USA found that supplementation with safflower oil improves glycemic control and lipid levels, and reduces inflammation in women with Type 2 diabetes.

    In a previous study they found that the essential n-6 polyunsaturated fatty acid linoleic acid rich safflower decreases fasting glucose and fat mass in the trunk region. 

    For this 16-week study Martha Belury¬† and colleagues selected 35 postmenopausal women with Type 2 diabetes and assessed potential of safflower oil for improving glycemic control and other markers of metabolic dysregulation, such as C-reactive protein (CRP) and high-density lipoprotein (HDL) cholesterol.

    The women were given safflower oil 8 g or conjugated linoleic acid for 16 weeks each in a double masked crossover fashion. They received one supplement for 16 weeks and another for a further 16 weeks after a 4-week washout period. 

    Safflower oil supplementation was observed to reduce glycated hemoglobin and CRP by 0.64% and 13.6 mg/l, respectively and increased HDL cholesterol by 0.12 mmol/l.
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