Lifestyle intervention plays a pivotal role in diabetes management. A study published in ‘BMC Nutrition’ by the Department of Exercise Physiology, Faculty of Sport Sciences, Iran aimed to examine the 8-week separate and combined effects of aerobic training (AT) and pomegranate juice intake (PJI) on insulin resistance and serum levels of liver enzymes, liver enzymes, and insulin resistance in men with T2DM.

The study examined the alterations of anthropometric indices, insulin resistance, and liver enzymes in 40 middle-aged men (40–50) with type 2 diabetes. Participants were randomly assigned into four groups: AT+PJI (n = 10); AT (n = 10); PJI (n = 10), and control (C) (n = 10). The AT program consisted of 60–75% of maximum heart rate (HRmax), 40–60 min/day, and 3 days/wk. Participants in the PJI group consumed 240 ml of sugar or additive-free pomegranate juice daily for 8 weeks.

The results revealed that AT+PJI, PJI, and AT groups decreased anthropometric indices, HOMA-IR, and liver enzymes after 8 weeks. Due to the effect of combined AT+PJI in improving T2DM risk factors, it could be recommended for T2DM patients to prevent increased liver enzymes and insulin resistance.